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Updated: Aug 16, 2026

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma
Published on: March 30, 2018
Clivus lymphoma
C S Jung1, M Zimmermann, V Seifert
1Department of Neurosurgery, Johann-Wolfgang Goethe University, Frankfurt, Germany. c.s.jung@em.uni-frankfurt.de
Abstract:
Lymphoma as primary infiltration of the skull base, especially the clivus, is unusual and rare. However, increasing incidence of atypical lymphoma manifestations have been reported. As cranial base surgery becomes more common, it is important to be aware of lymphoma as a possible differential diagnosis of clivus lesions. This case presents a primary malignant lymphoma of the clivus, histologically confirmed after intra-operative MRI-guided transnasal-transsphenoidal biopsy.
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