[Sublingual vs subcutaneous immunotherapy]

Alfonso Olivé Pérez1

  • 1Institut Català de la Salud, Cap Besos, Barcelona, España.

Revista Alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)
|May 4, 2004
PubMed

At the end of the 1980 decade, the first reports about the use of oral and sublingual routes of immunotherapy were published. This article reviews some reports comparing sublingual vs subcutaneous immunotherapy.

Related Concept Videos

Insulin Formulations: Types and Delivery01:27

Insulin Formulations: Types and Delivery

Insulin preparations are categorized by their duration of action into short-acting and long-acting types. Two strategies are used to modify insulin's absorption and pharmacokinetic profile: slowing the absorption post-subcutaneous injection, or altering human insulin's amino acid sequence or protein structure. These changes retain the insulin's ability to bind to the insulin receptor, but alter its behavior in solution or after injection.
Short-acting insulins are divided into rapid-acting...
Insulin: Dosing Regimen and Adverse Effects01:16

Insulin: Dosing Regimen and Adverse Effects

Insulin-replacement therapy usually includes both long-acting insulin (basal) and short-acting insulin (to cater to postprandial needs). In a diverse group of type 1 diabetes patients, the average daily insulin dose is typically 0.5-0.7 units/kg body weight. However, obese patients and pubertal adolescents may need more due to insulin resistance.
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...