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PI*E Tripoli: a new allele in the alpha-1-antitrypsin system
1Department of Laboratory Medicine and Pathology, Hamad General Hospital, Doha, Qatar.
Human Heredity
|January 1, 1992
Abstract:
Genetic variants of the human serum alpha 1-antitrypsin (PI system) were analyzed in a population sample of 110 unrelated Libyans. Four common PI M variants and 3 rare ones, including a new anodal variant designated PI E Tripoli (PI ET) were identified. The estimated allele frequencies were: PI*M1 = 0.623; PI*M2 = 0.205; PI*M3 = 0.132; PI*M4 = 0.018; PI*ET = 0.005; PI*S = 0.005, and PI*T = 0.014.