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Urticaria and angioedema: an overview.
Donald A Dibbern1, Stephen C Dreskin
1Division of Allergy and Clinical Immunology, Oregon Health and Sciences University, 3181 SW Sam Jackson Park Drive, OP34, Portland, OR 97239-3098, USA.
Immunology and Allergy Clinics of North America
|May 4, 2004
Summary
Diagnosing chronic urticaria requires a detailed history and physical exam by a specialist. New, rigorously tested treatments are needed due to limited efficacy and side effects of current options.
Area of Science:
- Dermatology
- Immunology
- Allergy
Background:
- Urticaria (hives) presents diagnostic and therapeutic challenges.
- Current treatments like antihistamines have limited efficacy, while steroids and cyclosporine have significant side effects.
Purpose of the Study:
- To emphasize the importance of specialist evaluation for identifying urticaria causes.
- To highlight the need for rigorous testing of alternative urticaria treatments.
Main Methods:
- Detailed patient history taking.
- Physical examination by a specialist knowledgeable in urticarial diseases.
- Review of current treatment limitations.
Main Results:
- A thorough history and physical exam by a specialist are key to identifying underlying causes.
- Existing treatments for chronic urticaria are often insufficient.
- There is a significant need for evidence-based evaluation of anecdotal treatments.
Conclusions:
- Specialist-led evaluation is crucial for diagnosing urticaria.
- Further research is essential to develop effective and safe urticaria treatments.
- Randomized controlled trials are needed for novel therapies.