Chronic urticaria and thyroid disease

Because the association of thyroid disease with pruritus and urticaria dates back more than 50 years, many investigators have commented on the possible link between autoimmune thyroid disease and chronic urticaria. This article summarizes an evolving body of literature linking these two conditions and discusses potential mechanisms as to how they concomitantly occur. Treatment options used to manage and control the urticaria are discussed with a focus on how the thyroid gland may have a role in the possible mechanism leading to chronic urticaria in this setting and how thyroid hormone may contribute to resolution of this condition.