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06:39
Ultrasound Based Assessment of Coronary Artery Flow and Coronary Flow Reserve Using the Pressure Overload Model in Mice
Published on: April 13, 2015
Fractional flow reserve and complex coronary pathologic conditions
1Department of Physiology and Institute of Cardiovascular Science and Medicine, Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Pokfulam, Hong Kong. kthau@attglobal.net
European Heart Journal
|May 4, 2004
Summary
Fractional flow reserve (FFR) is a validated index for assessing coronary stenosis significance. This paper reviews the theory and clinical use of pressure-derived FFR in complex coronary interventions.
Area of Science:
- Cardiovascular medicine
- Interventional cardiology
- Physiology
Background:
- Fractional flow reserve (FFR) is a key metric in assessing coronary artery disease.
- Accurate stenosis assessment is crucial for guiding revascularization decisions.
Purpose of the Study:
- To provide an overview of the theoretical underpinnings of coronary pressure-derived FFR.
- To discuss the clinical applicability of FFR in complex coronary interventions.
Main Methods:
- Review of the theoretical basis of FFR calculation.
- Discussion of clinical case examples and guidelines.
Main Results:
- FFR is a well-validated index for physiologic significance of coronary stenosis.
- FFR aids in decision-making for complex coronary interventions.
Conclusions:
- FFR provides essential physiologic information beyond anatomical assessment.
- Understanding FFR theory and application optimizes patient outcomes in interventional cardiology.
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