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Updated: Aug 14, 2026

HPLC-based Assay to Monitor Extracellular Nucleotide/Nucleoside Metabolism in Human Chronic Lymphocytic Leukemia Cells
Published on: July 20, 2016
Treatment of chronic lymphocytic leukemia
Alessandra Ferrajoli1, Susan M O'Brien
1Department of Leukemia, The University of Texas, M. D. Anderson Cancer Center, Houston 77030-4009, USA.
Abstract:
Treatment options for patients with chronic lymphocytic leukemia have changed over the past two decades. This article reviews the experience accumulated with the use of alkylating agents alone and in combination; purine analogues alone and in combination and monoclonal antibodies such as rituximab, and alemtuzumab alone and in combination. The results obtained with different treatment strategies are summarized, compared, and reviewed.
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