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Related Experiment Videos

Accurate bidirectional saccade control by a single hemicortex.

Troy M Herter1, Daniel Guitton

  • 1Montreal Neurological Institute, 3801 University Street, Montreal, Quebec, Canada.

Brain : a Journal of Neurology
|May 8, 2004
PubMed
Summary
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Patients with hemidecortication can produce accurate ipsiversive saccades, demonstrating a single brain hemisphere

Area of Science:

  • Neuroscience
  • Ophthalmology
  • Cognitive Science

Background:

  • Normally, each brain hemisphere controls eye movements (saccades) to the opposite side (contralateral).
  • Following surgery removing one hemisphere (hemidecortication), the remaining hemisphere can direct saccades both away (contraversive) and towards (ipsiversive) itself.
  • Ipsiversive saccades in hemidecorticate patients are typically inaccurate due to blindness and lack of visual error signals.

Purpose of the Study:

  • To investigate if hemidecorticate patients can generate accurate ipsiversive saccades.
  • To determine if a single hemisphere can mediate accurate bidirectional eye movement control.
  • To explore the capacity for accurate ipsiversive saccade generation despite visual field deficits.

Main Methods:

Related Experiment Videos

  • A specialized task dissociated visual field deficits from saccade direction.
  • Patients fixated a central target, then a saccade target appeared in the intact visual field.
  • Eye movements tracked a moving fixation target into the blind visual field; saccades were then made to the remembered target location in darkness.

    • Main Results:

    • Hemidecorticate patients generated accurate ipsiversive saccades to remembered target locations.
    • Saccade accuracy in hemidecorticate patients matched that of normal control subjects.
    • This suggests a single hemisphere can control accurate eye movements in both directions.

    Conclusions:

    • A single remaining cerebral hemisphere can mediate accurate bidirectional saccade control.
    • This control is achieved through intact connections from the cortex to brainstem oculomotor structures.
    • The precise mechanisms for visual calibration of ipsiversive saccades in this context remain unclear.