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Published on: February 23, 2014
Invasive pneumococcal infection in a healthy infant caused by two different serotypes
Ana Lucia S Sgambatti de Andrade1, Fabiana Cristina Pimenta, Cristina Aparecida Borges Laval
1Institute of Tropical Pathology and Public Health, Federal University of Goiás, Goyania, Brazil. ana@iptsp.ufg.br
Abstract:
We present a case of invasive pneumococcal infection in a healthy 10-month-old infant from whom Streptococcus pneumoniae serotype 23F was isolated from the blood and serotype 23B was isolated from the cerebrospinal fluid. Both serotypes were penicillin nonsusceptible. Pulsed-field gel electrophoresis analysis demonstrated that the two serotypes had distinct DNA patterns, indicating that infection did not occur as a result of capsular transformation but as a result of a mixed infection with two distinct pneumococcal serotypes.
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