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Updated: Aug 24, 2026

Development of Heterogeneous Enantioselective Catalysts using Chiral Metal-Organic Frameworks (MOFs)
Published on: January 17, 2020
Asymmetric Michael reaction promoted by new chiral phase-transfer catalysts
Shigeru Arai1, Kazuyuki Tokumaru, Toyohiko Aoyama
1Graduate School of Pharmaceutical Sciences, Nagoya City University, Japan. arai@p.chiba-u.ac.jp
Abstract:
A catalytic asymmetric Michael reaction promoted by new chiral quaternary ammonium salts is described. The products are obtained with moderate ee (up to 75% ee), and the enantioselectivity is strongly dependent on both the substituents on the aromatic rings and the ammonium moiety in the catalysts.
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