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A primary hepatic plasma cell tumor in a dog
Mica Aoki1, Tetsujun Kim, Terumasa Shimada
1Laboratories of Veterinary Surgery, Graduate School of Veterinary Medicine, Osaka Prefecture University, Sakai, Japan.
The Journal of Veterinary Medical Science
|May 11, 2004
Summary
A Shetland sheep dog with liver plasma cell tumor showed hyperproteinemia and monoclonal gammopathy. Treatment resolved these conditions, indicating a primary liver origin for the tumor.
Area of Science:
- Veterinary Medicine
- Oncology
- Canine Health
Background:
- Hyperproteinemia and monoclonal gammopathy can indicate underlying neoplastic processes in dogs.
- Plasma cell tumors, while uncommon in the liver, can arise in various organs.
Observation:
- An 8-year-old Shetland sheep dog presented with elevated serum protein and a monoclonal gammopathy.
- A solid liver mass was identified and histologically confirmed as a plasma cell tumor.
Findings:
- Surgical resection and chemotherapy led to the normalization of serum protein levels.
- The monoclonal gammopathy resolved post-treatment, suggesting successful tumor ablation.
Implications:
- This case supports the liver as a primary site for plasma cell tumor development in dogs.
- Effective treatment strategies can lead to remission of hyperproteinemia and gammopathy associated with canine liver plasma cell tumors.