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A novel A-to-G mutation in circBDP1 alters adipocyte proliferation and differentiation and affects bovine carcass
Enhui Jiang1,2, Chiyuan Zhang1, Zhuoyuan He1
1College of Animal Science and Technology, Northwest A&F University, Yangling 712100, China.
Abstract:
Fat deposition in cattle, influenced by factors such as genetics, age, sex, and nutrition, plays a crucial role in determining growth rates, beef yield, and meat quality. Among these, genetics is the predominant factor (Kim et al., 2020; Xing et al., 2025). Research indicates a high heritability for visceral (36%) and subcutaneous (57%) fat (Fox et al., 2012). Gene mutations that affect adipocyte function are significant contributors to variations in fat deposition and meat quality (Mannen, 2011; Mwangi et al., 2019; Sun et al., 2023; Dementieva et al., 2024). Therefore, investigating genetic variations in fat-related genes is essential for enhancing cattle performance.
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