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Updated: Aug 4, 2026

Methyl-binding DNA capture Sequencing for Patient Tissues
Published on: October 31, 2016
Genetic and epigenetic analyses of MBD3 in colon and lung cancer
Y Zhu1, D J Harrison, S A Bader
1Sir Alastair Currie Cancer Research UK Laboratories, Division of Pathology, Molecular Medicine Centre, University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK.
Abstract:
MBD3: is a member of the methyl-CpG-binding domain family and is located on chromosome 19p13.3, a region of loss of heterozygosity in colon and lung cancers. We therefore screened samples for abnormalities in MBD3. Our results indicate that MBD3 is not a major target of genetic and epigenetic alteration in these cancers.
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