Related Experiment Video
Updated: Aug 6, 2026

Electroactive Polymer Nanoparticles Exhibiting Photothermal Properties
Published on: January 8, 2016
Penicillamine disulfide (PNS) and alkaline cations
Fabrizio Apruzzese1, Emilio Bottari, Maria Rosa Festa
1Dipartimento di Chimica, l'Università La Sapienza, P.le A. Moro 5, Box n. 34, Roma 62, 00185 Roma, Italy.
Abstract:
D-penicillamine disulfide (PNS) shows protolytic properties and is able to form complexes with cations, because it has two aminic groups and two carboxylic groups. The four protonation constants of its deprotonated species were determined by means of electromotive force (e.m.f.) measurements of a galvanic cell involving a glass electrode at 25 degrees C and in a constant ionic medium constituted by N(CH3)4Cl 3.00 or 1.00 mol dm-3. At 25 degrees C and in 3.00 mol dm-3 N(CH3)4Cl as ionic medium, equilibria taking place between PNS and lithium, sodium and potassium ions were investigated. Experimental data, again obtained from e.m.f. measurements, were explained by assuming the formation of species of the type MH2PNS ed M2H2PNS, where M indicates a cation. Stability constants for each proposed species were calculated. A comparison with cystine is discussed.
More Related Videos
11:04Ion Mobility-Mass Spectrometry Techniques for Determining the Structure and Mechanisms of Metal Ion Recognition and Redox Activity of Metal Binding Oligopeptides
Published on: September 7, 2019
07:24Preparation of Cross-Linked Sodium Alginate Microspheres with Different Metal Ions Using the Microfluidic Electrospray Technology
Published on: June 7, 2024
Related Concept Videos
Ionic Bonding and Electron Transfer
Direct-Acting Cholinergic Agonists: Pharmacokinetics
Anticholinesterase Agents: Poisoning and Treatment
Irreversible agents form a strong bond with the cholinesterase enzyme, making it inactive. The breakdown of the phosphorylated enzyme is slower than the...
Acid Mine Drainage
Secondary Spinal Cord Injury llI: Pathophysiology
Antiprotozoal Agents