Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The bacterial factor in hemorrhagic shock.

B F Rush1

  • 1Department of Surgery, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark.

Surgery, Gynecology & Obstetrics
|September 11, 1992
PubMed
Summary

Research shows that hemorrhagic, traumatic, septic, and burn shock share common pathways leading to cell damage. Blocking these pathways could treat multiple shock conditions.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Breast cancer: which paradigm?

Journal of surgical oncology·2000
Same author

Locoregional techniques in the treatment of hepatic tumors.

Journal of surgical oncology·1997
Same author

Breast cancer in the inner city: intensive efforts may be succeeding.

Journal of medicine·1996
Same author

A comparison of survival at different degrees of hemorrhagic shock in germ-free and germ-bearing rats.

Shock (Augusta, Ga.)·1995
Same author

Stomal seeding of head and neck cancer by percutaneous endoscopic gastrostomy tube placement.

Annals of surgical oncology·1995
Same author

A decade of training in surgical oncology.

Journal of surgical oncology·1995

Area of Science:

  • Physiology
  • Pathology
  • Biochemistry

Background:

  • Hemorrhagic shock, traumatic shock, septic shock, and burn shock are distinct clinical conditions.
  • Despite differing causes, a century of research suggests a common underlying pathophysiology.

Observation:

  • All investigated shock states result in cellular injury and subsequent cell death.
  • These detrimental cellular effects appear to be mediated by shared molecular and cellular mechanisms.

Findings:

  • A common set of cellular pathways is activated across various types of shock.
  • Identifying and targeting these shared pathways represents a unified therapeutic strategy.

Implications:

  • Therapeutic interventions aimed at blocking these common pathways may offer broad efficacy.
  • This approach could lead to novel treatments for multiple critical care conditions, improving patient outcomes.

Related Experiment Videos