Related Experiment Videos
Shock, sepsis, and the gut
1UMDNJ-New Jersey Medical School, Newark 07103.
New Jersey Medicine : the Journal of the Medical Society of New Jersey
|November 1, 1994
Summary
Bacteria move from the gut to the bloodstream after hemorrhagic shock. Research is ongoing to determine the role of this bacterial translocation in sepsis development.
Area of Science:
- Microbiology
- Sepsis Pathophysiology
- Trauma Research
Background:
- Bacterial translocation from the gut to systemic circulation is a known consequence of hemorrhagic shock in humans.
- The clinical significance of this translocation in the development of sepsis remains under investigation.
Purpose of the Study:
- To review current research on the role of gut bacterial translocation in sepsis following hemorrhagic shock.
- To synthesize findings from UMDNJ-New Jersey Medical School research in this area.
Main Methods:
- Literature review of existing studies.
- Analysis of research conducted at UMDNJ-New Jersey Medical School.
Main Results:
- Established phenomenon of bacterial translocation post-hemorrhagic shock.
- Ongoing evaluation of the link between bacterial translocation and sepsis.
Conclusions:
- Bacterial translocation is a confirmed event after hemorrhagic shock.
- Further research is required to fully elucidate its contribution to sepsis pathogenesis.