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Updated: Aug 24, 2026

Imaging Ca2+ Dynamics in Cone Photoreceptor Axon Terminals of the Mouse Retina
Published on: May 6, 2015
Directional imaging of the retinal cone mosaic
Brian Vohnsen1, Ignacio Iglesias, Pablo Artal
1Laboratorio de Optica, Universidad de Murcia, Campus de Espinardo (Edificio C), 30071 Murcia, Spain. vohnsen@um.es
Abstract:
We describe a near-IR scanning laser ophthalmoscope that allows the retinal cone mosaic to be imaged in the human eye in vivo without the use of wave-front correction techniques. The method takes advantage of the highly directional quality of cone photoreceptors that permits efficient coupling of light to individual cones and subsequent detection of most directional components of the backscattered light produced by the light-guiding effect of the cones. We discuss details of the system and describe cone-mosaic images obtained under different conditions.
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