CT detection of acute myocardial infarction

Amy Gosalia1, Linda B Haramati, Milan P Sheth

  • 1Department of Radiology, Albert Einstein College of Medicine, Montefiore Medical Center, 111 E 210 Street, Bronx, NY 10467, USA.

Insights

Contrast-enhanced CT can detect acute myocardial infarction (MI) by identifying decreased left ventricular enhancement. This imaging technique shows MI in a pattern consistent with coronary artery distribution.

Area of Science:

  • Cardiovascular Imaging
  • Radiology
  • Medical Diagnostics

Background:

  • Acute myocardial infarction (MI) diagnosis relies on various methods.
  • Systematic assessment of contrast-enhanced CT for MI detection is lacking.
  • Evaluating novel imaging techniques is crucial for timely diagnosis.

Purpose of the Study:

  • To assess the efficacy of contrast-enhanced computed tomography (CT) in detecting acute myocardial infarction (MI).
  • To determine if contrast-enhanced CT findings correlate with coronary artery distribution in patients with MI.
  • To establish the diagnostic capability of contrast-enhanced helical chest CT for acute MI.

Main Methods:

  • Retrospective analysis of 18 patients (10 women, 8 men; mean age 66 years) with confirmed initial MI.
  • Patients underwent contrast-enhanced single-detector helical chest CT within one month post-MI.
  • Imaging data were analyzed for patterns of myocardial enhancement.

Main Results:

  • Acute myocardial infarction (MI) was identified as a region of reduced left ventricular myocardial enhancement on contrast-enhanced CT.
  • The observed pattern of decreased enhancement corresponded to specific coronary arterial territories.
  • The study demonstrated the feasibility of detecting MI using this imaging modality.

Conclusions:

  • Contrast-enhanced CT is a viable method for detecting acute myocardial infarction (MI).
  • Findings of decreased left ventricular myocardial enhancement on CT are indicative of MI.
  • The distribution of enhancement defects aligns with coronary artery anatomy, aiding in diagnosis.
Abstract

Related Concept Videos

Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
Acute Coronary Syndrome I: Introduction01:30

Acute Coronary Syndrome I: Introduction

Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
Blood Studies for Cardiovascular System I: Cardiac Biomarkers01:20

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
Myocarditis II: Clinical Features and Diagnostic Tests01:27

Myocarditis II: Clinical Features and Diagnostic Tests

Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
Imaging Studies for Cardiovascular System V: CT01:28

Imaging Studies for Cardiovascular System V: CT

Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...