Double C-H activation strategy for the asymmetric synthesis of C2-symmetric anilines
1Department of Chemistry, University at Buffalo, State University of New York, Buffalo, NY 14260-3000, USA. hdavies@acsu.buffalo.edu
Organic Letters
|May 21, 2004
Abstract:
Rh(2)(S-DOSP)(4)-catalyzed C-H activation to N,N-dimethylanilines is described. A double C-H activation was possible by using an excess of methyl aryldiazoacetate, and this provided a very direct approach to C(2)-symmetric anilines. [reaction--see text]
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