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Crural or pedal artery revascularisation for limb salvage: is it justified?
1Department of Cardiovascular and Thoracic Surgery, University Hospital of Liège, CHU du Sart-Tilman, Liège, Belgium. hvandamme@chu.ulg.ac.be
Insights
For patients with critical limb ischemia, limb-saving distal bypass surgery offers a viable alternative to primary amputation, improving quality of life and potentially offering cost-effectiveness.
Area of Science:
- Vascular Surgery
- Vascular Medicine
- Geriatric Medicine
Background:
- Increasing incidence of limb-threatening ischemia in aging populations.
- Peripheral arterial occlusive disease commonly affects infrainguinal and infragenicular vessels.
- Advances in vascular surgery enable reconstruction of crural and pedal vessels.
Purpose of the Study:
- To evaluate the feasibility and durability of infrapopliteal bypasses.
- To compare limb-saving distal bypass surgery with primary amputation for advanced limb-threatening ischemia.
- To assess the quality of life and cost-effectiveness of both treatment options.
Main Methods:
- Literature review of recent data on infrapopliteal bypasses.
- Analysis of studies considering quality of life outcomes.
- Cost-effectiveness assessment of limb-saving surgery versus amputation.
Main Results:
- Infrapopliteal bypass surgery is feasible and durable in select patients.
- Limb-saving surgery can improve quality of life compared to amputation.
- Cost-effectiveness analysis indicates potential benefits of bypass in certain scenarios.
Conclusions:
- Distal bypass surgery is a viable option for limb salvage in chronic critical limb ischemia.
- Treatment decisions should consider patient frailty, comorbidities, and patient-reported outcomes.
- Further research on long-term outcomes and cost-effectiveness is warranted.
Abstract:
With the ageing of population, the incidence of limb-threatening ischemia increases. In chronic critical limb ischemia, peripheral arterial occlusive disease almost always involves infrainguinal and infragenicular vessels. Fortunately, recent advances in vascular surgery made arterial reconstruction of crural and pedal vessels possible. Should crural or pedal bypass surgery be offered to these frail, polyvascular patients, or is primary amputation a preferable treatment option in case of advanced limb-threatening ischemia? In order to answer this controversial question, the author analysed recent literature data on the feasibility and durability of infrapopliteal bypasses. The quality of life was also considered as an outcome measure. Finally, the cost-effectiveness of both treatment modalities (limb-saving distal bypass versus primary amputation) was assessed.
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