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Using child reported respiratory symptoms to diagnose asthma in the community
1Department of Community & Family Medicine, The Chinese University of Hong Kong, School of Public Health, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China. iyu@cuhk.edu.hk
Aims:
To study how respiratory symptoms reported by children, with or without spirometry, could help to discriminate those with asthma from those without.
Methods:
Respiratory symptoms (frequent cough, frequent phlegm, and wheezing) reported by 1646 schoolchildren (aged 8-12 years) in a respiratory questionnaire and the FEV1:FVC ratio measured with spirometry (at three different cut-off values of 0.70, 0.75, and 0.80) were compared against the criterion standard of a physician diagnosis of asthma reported by the parents.
Results:
The overall prevalence of asthma was 6%; more boys had asthma. Wheezing had the best discriminating ability among the three symptoms and a cut-off point at 75% was best for the FEV1:FVC ratio. Combining wheezing with an FEV1:FVC ratio <75% gave the highest discriminating ability of 83%. If the tests were applied to hypothetical populations with higher prevalence ratios of asthma, the added value of the FEV1:FVC ratio became less apparent.
Conclusion:
Respiratory symptoms, especially wheezing, reported by children had good discriminating ability for asthma and could be adopted for opportunistic screening in the primary care settings.
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