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Updated: Aug 24, 2026

A Patient-Derived Xenograft Model for Venous Malformation
Published on: June 15, 2020
Glomangioma of the upper limb associated with hypoplastic-dysplastic superficial venous system
D G Parthenis1, K I Paraskevas, D N Staramos
1Department of Vascular Surgery, Radiology and Pathology, Konstantopoulio Agia Olga General Hospital, Athens, Greece.
Abstract:
The diagnosis and therapy of vascular malformations is difficult. An important factor, which influences the therapeutic approach, is the complicated vascular network of the lesions. The frequent involvement of various structures (muscles, bones or other organs) makes the surgical intervention arduous. Glomus tumors are rare, symptomatic (painful) lesions, with dimensions ranging 3-10 mm and usually subungual location, which need radical resection as a therapy. The case we present is the first one where a glomus tumor presents as a hypoplastic-dysplastic superficial venous system, located parallel to the normal superficial venous system of the left upper extremity, resembling a form of varicosities. The atypical clinical presentation and the unique morphology classify this case in a very limited category of nosological entities.
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