Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cell adhesion and angiogenesis.

S Strömblad1, D A Cheresh

  • 1Dept of Immunology, The Scripps Research Institute, La Jolla, CA 92037, USA. staffans@scripps.edu

Trends in Cell Biology
|December 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Correction: The atypical ubiquitin ligase RNF31 stabilizes estrogen receptor α and modulates estrogen-stimulated breast cancer cell proliferation.

Oncogene·2018
Same author

RING finger protein 31 promotes p53 degradation in breast cancer cells.

Oncogene·2015
Same author

The atypical ubiquitin ligase RNF31 stabilizes estrogen receptor α and modulates estrogen-stimulated breast cancer cell proliferation.

Oncogene·2014
Same author

EGFR-dependent pancreatic carcinoma cell metastasis through Rap1 activation.

Oncogene·2011
Same author

Oncogenic Ras/Src cooperativity in pancreatic neoplasia.

Oncogene·2011
Same author

Regulation of angiogenesis: apoptotic cues from the ECM.

Oncogene·2008
Same journal

Horizontal transfer of mitochondria in cancer: The physiology reborn in disease?

Trends in cell biology·2026
Same journal

Spindle errors: A stress test for epithelial robustness.

Trends in cell biology·2026
Same journal

Multicellular ecosystems: Linking cellular diversity to tissue function and disease.

Trends in cell biology·2026
Same journal

Orchestrating the signaling-bias at the protease-activated receptor, PAR1.

Trends in cell biology·2026
Same journal

Crashing by design: Utilizing DNA damage for MCC differentiation.

Trends in cell biology·2026
Same journal

The value of a shared lab: Our insights.

Trends in cell biology·2026
See all related articles

Cell adhesion is crucial for blood vessel formation (angiogenesis). This review highlights cell-matrix and cell-cell interactions, focusing on integrin alphavbeta3

Area of Science:

  • Molecular Biology
  • Cell Biology
  • Biochemistry

Background:

  • Cell adhesion mechanisms are fundamental to angiogenesis.
  • Cell-matrix and cell-cell interactions are key components of blood vessel formation.

Purpose of the Study:

  • To summarize the role of cell-adhesion events in angiogenesis.
  • To discuss the specific function of integrin alphavbeta3 in vascular development.

Main Methods:

  • Literature review of cell adhesion in angiogenesis.
  • Analysis of integrin alphavbeta3's role in vascular cells.

Main Results:

  • Cell adhesion, including cell-matrix and cell-cell interactions, is vital for angiogenesis.
  • Integrin alphavbeta3 significantly influences vascular cell survival, proliferation, and invasion during angiogenesis.

Related Experiment Videos

Conclusions:

  • Understanding cell adhesion mechanisms, particularly integrin alphavbeta3, is critical for studying angiogenesis.
  • Targeting integrin alphavbeta3 may offer therapeutic potential in vascular diseases.