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Updated: Aug 24, 2026

Multi-timescale Microscopy Methods for the Characterization of Fluorescently-labeled Microbubbles for Ultrasound-Triggered Drug Release
Published on: June 12, 2021
Microbubble contrast agents for echocardiography: rationale, composition, ultrasound interactions, and safety
Ajit Raisinghani1, Patrick Rafter, Patrick Phillips
1Cardiology Division, University of California-San Diego, 200 West Arbor Drive, San Diego, CA 92103-8411, USA.
Abstract:
Imaging the small blood vessels within the myocardium, which contains only a small fraction of the total coronary blood volume, is a significant challenge for ultrasound imaging. Recent advances in microbubble design and ultrasound technology have improved our ability to image the microcirculation. It is essential to understand the fundamentals of microbubble behavior in an ultrasound field and how it impacts technology and safety.
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