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Related Experiment Videos

High-altitude illness.

Scott A Gallagher1, Peter H Hackett

  • 1Department of Emergency Medicine, Aspen Valley Hospital, CO 81611, USA. docgliv@excite.com

Emergency Medicine Clinics of North America
|May 28, 2004
PubMed
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High altitude travel requires acclimatization to prevent altitude sickness, including acute mountain sickness (AMS), cerebral edema (HACE), and pulmonary edema (HAPE). Early recognition and prevention are key to managing these serious, yet avoidable, conditions.

Area of Science:

  • Environmental Medicine
  • Physiology
  • Altitude Research

Background:

  • High altitude travel exposes individuals to hypobaric hypoxia.
  • Failure to acclimatize to altitude can lead to serious health issues.
  • High-altitude illness encompasses acute mountain sickness (AMS), high-altitude cerebral edema (HACE), and high-altitude pulmonary edema (HAPE).

Purpose of the Study:

  • To review the pathophysiology of high-altitude illness.
  • To emphasize the importance of recognizing and preventing altitude-related maladies.
  • To inform practitioners about managing travelers to high altitudes.

Main Methods:

  • Review of existing literature on high-altitude physiology and illness.
  • Analysis of the mechanisms underlying AMS, HACE, and HAPE.

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  • Synthesis of information on diagnosis, treatment, and prevention.

    • Main Results:

    • High-altitude illnesses result from capillary leakage in the brain or lungs.
    • These conditions are preventable with proper acclimatization and medical awareness.
    • Morbidity and mortality are significant but avoidable.

    Conclusions:

    • Practitioners must be knowledgeable about high-altitude illness.
    • Early symptom recognition, prompt therapy, and preventative measures are crucial.
    • Effective management strategies can mitigate the risks associated with high-altitude travel.