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Black tea increases coronary flow velocity reserve in healthy male subjects
Kumiko Hirata1, Kenei Shimada, Hiroyuki Watanabe
1Department of Medicine, Division of Cardiology, College of Physicians & Surgeons, Columbia University, New York, NY, USA.
Insights
Black tea consumption significantly improves coronary flow velocity reserve (CFVR), a measure of coronary circulation function. This study demonstrates acute benefits of black tea on heart blood vessel health.
Area of Science:
- Cardiology
- Cardiovascular Physiology
- Nutritional Science
Background:
- Epidemiological studies indicate tea consumption is linked to reduced cardiovascular event risk.
- Clinical evidence on tea's direct impact on coronary circulation is lacking.
- Coronary flow velocity reserve (CFVR) is a key indicator of coronary circulatory function.
Purpose of the Study:
- To investigate the acute effects of black tea consumption on coronary flow velocity reserve (CFVR).
- To compare the impact of black tea versus caffeine on coronary circulation.
- To utilize transthoracic Doppler echocardiography (TTDE) for CFVR assessment.
Main Methods:
- A double-blind, crossover study involving 10 healthy male volunteers.
- Measurement of coronary flow velocity in the left anterior descending coronary artery using TTDE.
- Assessment of CFVR at baseline and during hyperemia induced by adenosine triphosphate infusion, before and after consuming black tea or caffeine.
Main Results:
- Two-way ANOVA revealed significant effects of beverage type and consumption timing on CFVR (p = 0.001).
- Black tea consumption led to a significant increase in CFVR (4.5 ± 0.9 to 5.2 ± 0.9, p < 0.0001).
- The CFVR ratio was significantly higher after black tea consumption compared to caffeine (1.18 ± 0.07 vs. 1.04 ± 0.08, p = 0.002).
Conclusions:
- Acute consumption of black tea enhances coronary vessel function.
- The improvement in coronary circulation is evidenced by a significant increase in CFVR.
- Black tea demonstrates a more pronounced effect on CFVR compared to caffeine.
Abstract:
Epidemiologic studies suggest that tea consumption decreases the risk for cardiovascular events. However, there has been no clinical report examining the effects of tea consumption on coronary circulation. The purpose of this study was to evaluate the effects of black tea on coronary flow velocity reserve (CFVR) using transthoracic Doppler echocardiography (TTDE). This was a double-blind crossover study of 10 healthy male volunteers conducted to compare the effects of black tea and caffeine on coronary circulation. The coronary flow velocity of the left anterior descending coronary artery was measured at baseline and at hyperemia during adenosine triphosphate infusion by TTDE to determine CFVR. The CFVR ratio was defined as the ratio of CFVR after beverage consumption to CFVR before beverage consumption. All data were divided into 2 groups according to beverage type: group T (black tea) and group C (caffeine). Two-way analysis of variance showed a significant group effect and interaction in CFVR before and after beverage consumption (p = 0.001). CFVR significantly increased after tea consumption in group T (4.5 +/- 0.9 vs 5.2 +/- 0.9, p <0.0001). The CFVR ratio of group T was larger than that of group C (1.18 +/- 0.07 vs 1.04 +/- 0.08, p = 0.002). Acute black tea consumption improves coronary vessel function, as determined by CFVR.
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