Aortic calcification detected in a mass chest screening program using a mobile helical computed tomography unit.

Yasutaka Itani1, Shigeru Watanabe, Yoshiaki Masuda

  • 1The Society of Thoracic CT Screening, Tokyo, Japan. itani-y@mtg.biglobe.ne.jp

Insights

Calcification in the thoracic aorta, detected via mobile CT screening, is linked to coronary artery disease (CAD). This finding helps assess CAD risk in asymptomatic individuals.

Area of Science:

  • Cardiology
  • Radiology
  • Public Health

Background:

  • Aortic arch calcification (AAC) is linked to coronary artery disease (CAD).
  • The association between risk factors, CAD, and aortic calcification detected via mobile CT screening is not well understood.

Purpose of the Study:

  • To investigate the relationship between risk factors, CAD, and thoracic aortic calcification (TAC) detected during mass screening using mobile helical CT.
  • To determine if TAC detected during mass screening can serve as a marker for CAD risk.

Main Methods:

  • A total of 2,623 subjects underwent mass screening using a mobile helical CT unit for lung cancer and tuberculosis.
  • Data collected included demographics, risk factors (hypertension, smoking), and CT findings of aortic calcification (aortic arch, ascending aorta, descending aorta).
  • Statistical analysis was performed to assess the association between risk factors, CAD, and TAC, and the odds ratio of TAC for patients with CAD.

Main Results:

  • Calcification was observed in 19.6% of the aortic arch, 2.7% of the ascending aorta, and 10.1% of the descending aorta.
  • Aortic calcification frequency increased with age in both genders.
  • Hypertension and smoking were significantly associated with thoracic aortic calcification. A significant relationship was found between CAD and aortic calcification, with increased odds of aortic calcification correlating with more calcified segments.

Conclusions:

  • Detection of thoracic aortic calcification during mass chest screening with mobile helical CT is a valuable tool.
  • This method can be utilized to effectively evaluate the risk of coronary artery disease in the screened population.
Abstract

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