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Updated: Aug 24, 2026

Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
Published on: August 28, 2018
Aortic calcification detected in a mass chest screening program using a mobile helical computed tomography unit.
Yasutaka Itani1, Shigeru Watanabe, Yoshiaki Masuda
1The Society of Thoracic CT Screening, Tokyo, Japan. itani-y@mtg.biglobe.ne.jp
Insights
Calcification in the thoracic aorta, detected via mobile CT screening, is linked to coronary artery disease (CAD). This finding helps assess CAD risk in asymptomatic individuals.
Area of Science:
- Cardiology
- Radiology
- Public Health
Background:
- Aortic arch calcification (AAC) is linked to coronary artery disease (CAD).
- The association between risk factors, CAD, and aortic calcification detected via mobile CT screening is not well understood.
Purpose of the Study:
- To investigate the relationship between risk factors, CAD, and thoracic aortic calcification (TAC) detected during mass screening using mobile helical CT.
- To determine if TAC detected during mass screening can serve as a marker for CAD risk.
Main Methods:
- A total of 2,623 subjects underwent mass screening using a mobile helical CT unit for lung cancer and tuberculosis.
- Data collected included demographics, risk factors (hypertension, smoking), and CT findings of aortic calcification (aortic arch, ascending aorta, descending aorta).
- Statistical analysis was performed to assess the association between risk factors, CAD, and TAC, and the odds ratio of TAC for patients with CAD.
Main Results:
- Calcification was observed in 19.6% of the aortic arch, 2.7% of the ascending aorta, and 10.1% of the descending aorta.
- Aortic calcification frequency increased with age in both genders.
- Hypertension and smoking were significantly associated with thoracic aortic calcification. A significant relationship was found between CAD and aortic calcification, with increased odds of aortic calcification correlating with more calcified segments.
Conclusions:
- Detection of thoracic aortic calcification during mass chest screening with mobile helical CT is a valuable tool.
- This method can be utilized to effectively evaluate the risk of coronary artery disease in the screened population.
Background:
There is a significant relationship between calcification of the aortic arch (Arch) detected by chest X-ray examination and coronary artery disease (CAD), but the relationship between risk factors, CAD and aortic calcification detected during a mass screening program using a mobile helical computed tomography (CT) unit remains unknown.
Methods And Results:
In total 2,623 subjects (1,347 men, and 1,276 women; mean age, 52.9+/-13.8) underwent an examination for lung cancer and tuberculosis using a mobile helical CT unit. The frequency of calcification was 19.6% in the Arch, 2.7% in the ascending aorta, and 10.1% in the descending aorta, values that were positively associated with age in both genders. Hypertension and smoking were significantly related to calcification of the thoracic aorta. There was a significant relationship between CAD and aortic calcification. The odds ratio of aortic calcification for patients with CAD increased as the number of calcified segments increased.
Conclusions:
These results suggest that detection of calcification in the thoracic aorta during a mass chest screening using a mobile helical CT unit can be used to evaluate the risk of CAD.
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