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Vascular complications following coronary intervention correlate with long-term cardiac events
Pramod K Kuchulakanti1, Lowell F Satler, William O Suddath
1Division of Cardiology, Washington Hospital Center, Washington, DC 20010, USA.
Insights
Peripheral vascular complications (PVCs) after percutaneous coronary interventions (PCI) significantly increase in-hospital and one-year risks for myocardial infarction, death, and need for coronary artery bypass grafting.
Area of Science:
- Cardiology
- Vascular Medicine
- Interventional Cardiology
Background:
- Peripheral vascular complications (PVCs) are a known risk following percutaneous coronary interventions (PCI).
- Understanding the long-term consequences of PVCs post-PCI is crucial for patient management.
Purpose of the Study:
- To investigate the in-hospital and late outcomes of patients who developed PVCs after PCI.
- To identify PVC as a predictor of mortality following PCI.
Main Methods:
- Retrospective analysis of 10,669 patients undergoing PCI between 1995 and 2002.
- Comparison of complication rates between patients with and without PVC post-PCI.
- Multivariate analysis to assess predictors of 1-year mortality.
Main Results:
- 10.27% of patients experienced PVC post-PCI.
- Patients with PVC had significantly higher in-hospital rates of Q-wave myocardial infarction (MI), coronary artery bypass grafting (CABG), and death.
- At 1-year follow-up, PVC patients showed increased rates of MI, death, and CABG, with PVC being a predictor of 1-year mortality.
Conclusions:
- Peripheral vascular complications post-PCI are associated with substantially worse in-hospital and late outcomes.
- Minimizing PVC during PCI and vigilant follow-up are essential for patients experiencing these complications.
Abstract:
We aimed to study the consequences and late outcomes of patients who experienced peripheral vascular complications (PVCs) following percutaneous coronary interventions (PCI). A retrospective analysis of the medical records of 10,669 patients who underwent PCI and experienced PVC between 1995 and 2002 was conducted. One thousand ninety-six patients (10.27% of the study cohort) had PVC post-PCI. After PCI, patients with PVC had higher rates of in-hospital complications (P < 0.001) when compared to patients without PVC, including Q-wave myocardial infarction (MI; 1.2% vs. 0.3%), coronary artery bypass grafting (CABG; 3.8% vs. 0.6%), and death (4.0% vs. 1.0%). At 1-year follow-up, late complications of MI (37.4% vs. 25.4%), non-Q-wave MI (34.9% vs. 22.7%), death (12.9% vs. 5.9%), and CABG (5.7% vs. 4.5%) were higher (< 0.001) in patients with PVC compared to those without. Multivariate analysis identified PVC as a significant predictor of 1-year mortality (P = 0.045). This study underscores the need to make diligent efforts to minimize PVC and follow up these patients for future coronary events.
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