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Perforated Patch-clamp Recording of Mouse Olfactory Sensory Neurons in Intact Neuroepithelium: Functional Analysis of Neurons Expressing an Identified Odorant Receptor
10:16

Perforated Patch-clamp Recording of Mouse Olfactory Sensory Neurons in Intact Neuroepithelium: Functional Analysis of Neurons Expressing an Identified Odorant Receptor

Published on: July 13, 2015

Olfactory receptor gene expression in tiger salamander olfactory epithelium

James E Marchand1, Xinhai Yang, Dona Chikaraishi

  • 1Department of Anesthesia, Tufts-New England Medical Center and Tufts University School of Medicine, Boston, Massachusetts 02111, USA. james.marchand@tufts.edu

The Journal of Comparative Neurology
|June 3, 2004
PubMed
Summary

Tiger salamanders reveal conserved olfactory coding principles. Researchers identified novel odorant receptor genes and mapped their expression patterns in the olfactory epithelium, offering insights into vertebrate smell.

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Olfaction01:25

Olfaction

The sense of smell is achieved through the activities of the olfactory system. It starts when an airborne odorant enters the nasal cavity and reaches olfactory epithelium (OE). The OE is protected by a thin layer of mucus, which also serves the purpose of dissolving more complex compounds into simpler chemical odorants. The size of the OE and the density of sensory neurons varies among species; in humans, the OE is only about 9-10 cm2.
The olfactory receptors are embedded in the cilia of the...