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Intra-Peritoneal Transplantation for Generating Acute Myeloid Leukemia in Mice
Published on: January 6, 2023
[Hepatosplenic candidiasis in acute myeloid leukemia]
A Larregina1, B Bartoletti, H Romano
1Hospital Municipal de Agudos Dr Leónidas Lucero, Servicios de Hematología, Hemoterapia, Clínica Medica y Laboratorio Central, Estomba 968, 8000 Bahía Blanca, Argentina. gdomi@ciudad.com.ar
Abstract:
Chronic diseminated candidiasis--mainly its hepatosplenic form- is one of the most characteristic invasive infection due to Candida in haematological patients. A case is presented of a 31 year old man admitted to the Clinical Department with acute mieloid leukosis M2, showing febrile neutropenia after induction and consolidation chemotherapy. Hepatoesplenic candidiasis was diagnosed and confirmed by computered axial tomography (CAT) and hepatic biopsy; amphotericin B followed by liposome encapsuled amphotericin B up to complete a total dose of 4 g was used for treatment. The patient was discharged waiting for bone marrow transplantation. Early suspicion of hepatosplenic candidiasis helps to select a rapid diagnosis method and an effective treatment.
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