Related Experiment Videos
Microcolins A and B, new immunosuppressive peptides from the blue-green alga Lyngbya majuscula
F E Koehn1, R E Longley, J K Reed
1Division of Biomedical Marine Research, Harbor Branch Oceanographic Institution, Inc., Ft. Pierce, Florida 34946.
Journal of Natural Products
|May 1, 1992
Abstract:
Microcolin A [1] and microcolin B [2] are new immunosuppressive lipopeptides isolated from a Venezuelan sample of the blue-green alga Lyngbya majuscula. The microcolins are potent inhibitors of the murine mixed lymphocyte response and murine P-388 leukemia in vitro. Isolation and structure elucidation of 1 and 2 by nmr, mass spectral, and chemical methods are described.