Related Experiment Video
Updated: Aug 24, 2026

Chromosome Preparation From Cultured Cells
Published on: January 28, 2014
A cytogenetic register of down syndrome in Lebanon
1Department of Laboratory Medicine and Pathology, American University of Beirut Medical Center, Beirut, Lebanon. lailaz@aub.edu.lb
Objectives:
To provide data on the cytogenetics and epidemiology of Down syndrome in our community.
Methods:
All cases of Down syndrome diagnosed cytogenetically were entered over a period of 5 years together with data regarding age at referral, parental ages and parity.
Results:
A total of 280 cases were entered. In postnatal cases, the mean maternal age was 32.19 years and 41.5% of mothers were over 35 years. Only 47.3% of Down syndrome children were diagnosed at less than 1 month of age. The male to female sex ratio of 1.66 is significantly more elevated than that reported in larger registers.
Conclusions:
Because of problems inherent to Lebanon, this register does not have a high level of ascertainment, however it appears that the emphasis in a potential prevention programme should be placed on education, information and family planning.
More Related Videos
09:16Array Comparative Genomic Hybridization (Array CGH) for Detection of Genomic Copy Number Variants
Published on: February 21, 2015
08:22A Robust Polymerase Chain Reaction-based Assay for Quantifying Cytosine-guanine-guanine Trinucleotide Repeats in Fragile X Mental Retardation-1 Gene
Published on: September 16, 2019
Related Concept Videos
Karyotyping
Karyotyping
Meiosis I
Nondisjunction
Nondisjunction
Nondisjunction