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Updated: Aug 24, 2026

Temperature-Controlled Assembly and Characterization of a Droplet Interface Bilayer
Published on: April 19, 2021
Zn(II)-induced conformational control of amphiphilic cavitands in langmuir monolayers
Markus Frei1, Federica Marotti, Francois Diederich
1Laboratorium fur Organische Chemie, ETH-Honggerberg, CH-8093 Zurich, Switzerland.
Abstract:
The reversible switching from the C(4v)-symmetric vase to the C(2v)-symmetric kite conformation of an amphiphilic resorcin[4]arene cavitand was induced by Zn(II) ion coordination. Langmuir monolayers were obtained of both conformers with the area per molecule increasing dramatically from 120 A(2) for the vase to 270 A(2) for the kite form. (1)H NMR spectroscopy in chloroform solution supports the formation of a stoichiometric kite-cavitand[radical dot](Zn(II))(2) complex, with the metal ions coordinating to pairs of neighbouring quinoxaline N-atoms.
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