[Expression of soluble intercellular adhesion molecule-1 in peri-implant sulcular fluid]

To investigate the expression of soluble intercellular adhesion molecule-1(sICAM-1) in peri-implant sulcular fluid (PISF) of different health conditions.

According to the health condition and plaque adhesion around dental implant, 51 titanium implants of 30 partly edentulous patients were divided into 3 groups: healthy group(H), gingivalis group(G) and peri-implantitis group(P). The clinical parameters included peri-implant pocket depth(PPD), gingival blood index (GBI), modified plaque index (mPLI) and sICAM-1. We used periopaper strips to collect PISF and an ELISA technique to measure the levels of sICAM-1.

The PPD levels of H, G and P groups were (2.64 +/- 1.00) mm, (3.65 +/- 0.60) mm and (4.39 +/- 1.46) mm respectively. The sICAM-1 levels in the three groups were (348.10 +/- 313.27) ng/ml, (898.30 +/- 501.14) ng/ml and (1149.36 +/- 1035.78) ng/ml. The sICAM-1 levels of PISF in the inflammatory groups and plaque adhesion groups were significantly higher than that in the healthy group and non-plaque adhesion group (P < 0.05). The PPD level in inflammatory groups was also significantly higher than that in healthy group.

Both the patients with peri-implantitis and the healthy controls showed the presence of sICAM-1 in PISF. Plaque accumulation might trigger the up-regulation of sICAM-1 levels, and the onset of inflammation would enhance the up-trend.