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Measuring Exocytosis in Neurons Using FM Labeling
Published on: November 30, 2006
Using FM1-43 to study neuropeptide granule dynamics and exocytosis
Audrey C Brumback1, Janet L Lieber, Joseph K Angleson
1Department of Biological Sciences, University of Denver, Denver, CO 80208, USA.
Methods (San Diego, Calif.)
|June 9, 2004
Abstract:
In the study of neuropeptide secretion and membrane trafficking, the fluorescent dye FM1-43 provides the ability to label selectively those structures that are undergoing exocytosis and endocytosis in living cells in real time. This review describes the unique properties of the FM dyes that make them ideal for studying neuropeptide granule dynamics and discusses various techniques that take advantage of FM dyes.
