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Iron deficiency anemia in children with exstrophy of the cloaca
S Young Yim1, S Young Yim, W O Walker
1Department of Physical Medicine and Rehabilitation, Ajou University School of Medicine, Suwon, Korea.
Insights
Iron deficiency anemia (IDA) affects 20% of children with exstrophy of the cloaca (EC). Management requires monitoring and treating IDA, especially when linked to short-bowel syndrome, for comprehensive care.
Area of Science:
- Pediatric Surgery
- Hematology
- Clinical Nutrition
Background:
- Exstrophy of the cloaca (EC) is a rare congenital anomaly.
- Iron deficiency anemia (IDA) is a common comorbidity in pediatric populations.
- The relationship between EC and IDA requires further investigation.
Purpose of the Study:
- To determine the prevalence of IDA in children with EC.
- To describe the clinical characteristics of IDA in this cohort.
- To inform clinical management strategies for EC patients.
Main Methods:
- Retrospective review of clinical records.
- Analysis of 25 children diagnosed with EC.
- Evaluation for the presence and characteristics of IDA.
Main Results:
- Twenty percent (5 of 25) of children with EC presented with IDA.
- IDA diagnosis occurred between 1.9 and 13.0 years of age.
- Four cases of IDA were associated with iron malabsorption due to short-bowel syndrome, requiring prolonged iron supplementation.
Conclusions:
- IDA is a significant concern in children with EC.
- Early monitoring and management of IDA are crucial for EC patients.
- Short-bowel syndrome in EC can complicate IDA treatment, necessitating extended iron therapy.
Abstract:
The clinical records of twenty-five children with exstrophy of the cloaca (EC) were retrospectively reviewed to evaluate the prevalence and the clinical characteristics of iron deficiency anemia (IDA). Five of the 25 children with EC (20 %) exhibited IDA at some point. Their ages at the time of diagnosis were between 1.9 and 13.0 years. In the four cases where IDA was thought to be related to iron malabsorption secondary to short-bowel syndrome, its treatment required longer periods of iron supplementation to correct the anemia and to restore the total body iron stores. Physicians caring for children with EC should monitor for and treat IDA as part of a comprehensive management plan.
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