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A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
Published on: October 4, 2019
(+)-Bornyl piperate, a new monoterpene ester from Piper aff. pedicellatum roots
Thitima Rukachaisirikul1, Samran Prabpai, Palangpon Kongsaeree
1Department of Chemistry, Faculty of Science, Ramkhamhaeng University, Bangkok, Thailand. thitima@ram1.ru.ac.th
Abstract:
A new monoterpene ester, (+)-bornyl piperate was isolated from the underground roots of Piper aff. pedicellatum and its structure was elucidated on the basis of spectroscopic evidence and confirmed by X-ray analysis. The compound crystallizes in the triclinic space group P1 with a=7.3232(4) A, b=11.4705(7) A, c=23.2520(14) A, V=1943.6(2) A(3). This compound showed an antituberculosis activity against Mycobacterium tuberculosis (H(37)Ra strain) with the minimum inhibitor concentration (MIC) of 25 microg/ml.
