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Digital signal processor-based real-time optical Doppler tomography system.

Shikui Yan1, Daqing Piao, Yueli Chen

  • 1Electrical & Computer Engineering Department, University of Connecticut, 371 Fairfield Road U11257, Storrs, CT 06269-2157, USA.

Journal of Biomedical Optics
|June 11, 2004
PubMed
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A new digital signal processor (DSP) unit enhances optical coherence tomography for real-time imaging of tissue and blood flow. This system accurately captures pulsatile blood flow and enables in vivo imaging.

Area of Science:

  • Biomedical Engineering
  • Medical Imaging
  • Optical Coherence Tomography

Background:

  • Optical coherence tomography (OCT) is a valuable imaging modality.
  • Real-time processing is crucial for advanced OCT applications, including Doppler flow imaging.
  • Integrating digital signal processing (DSP) can enhance OCT system capabilities.

Purpose of the Study:

  • To develop and evaluate a real-time data-processing and display unit for OCT systems.
  • To demonstrate the integration of a custom DSP module for enhanced Doppler blood flow imaging.
  • To showcase the flexibility of embedding advanced Doppler processing algorithms within the DSP module.

Main Methods:

  • A custom digital signal processor (DSP) module was designed and incorporated into a conventional optical coherence tomography (OCT) system.

Related Experiment Videos

  • Two advanced velocity estimation algorithms were embedded within the DSP module.
  • Experiments were conducted using Intralipid flow phantoms and in vivo rat abdominal blood flow imaging.

    • Main Results:

    • The DSP-based OCT system successfully performed real-time data processing and display.
    • Pulsatile blood flow, with rates of several hundred pulses per minute, was faithfully captured in M-scan mode.
    • In vivo imaging of a rat's abdominal blood flow was successfully demonstrated.

    Conclusions:

    • The developed DSP module significantly enhances OCT capabilities for real-time tissue structure and Doppler blood flow imaging.
    • The system's flexibility allows for the integration of advanced Doppler processing algorithms.
    • This technology holds promise for improved non-invasive blood flow assessment.