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Updated: Aug 23, 2026

Measurement of Factor V Activity in Human Plasma Using a Microplate Coagulation Assay
Published on: September 9, 2012
Effect of factor VIIIc levels in pediatric stroke patients
Emel Cangöz1, Gülhis Deda, Nejat Akar
1Ankara University, School of Medicine, Department of Pediatrics, Ankara, Turkey.
Abstract:
Twenty consecutive patients with ischemic stroke confirmed by magnetic resonance imaging and 40 healthy age-matched controls were enrolled in the study. Thirteen of the patients had an underlying disease and/or risk factors. Infection was the most common underlying factor (4 patients). Four patients had heterozygote FVL and 3 patients showed heterozygosity for PT 20210A. A weak positive association between FV1691A and high FVIIIc levels (r = -.110) was determined. Comparison of the prevalence of high FVIIIc levels in patients and healthy subjects with and without FVL/PT 20210 indicated that high FVIII levels are an independent risk factor.
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