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[Allergic rhinitis frequently impairs bronchial function].

Andrea Vizzaccaro1, Ignazio Cirillo, Eugenio Pallestrini

  • 1Reparto di Medicina ed Allergologia Respiratoria, Ospedale Principale Marina Militare, La Spezia.

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Summary
This summary is machine-generated.

Allergic rhinitis can worsen asthma by affecting its natural course. Treating co-existing upper airway issues is key for asthma patients unresponsive to standard therapies.

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Area of Science:

  • Explores the intricate relationship between upper and lower airway diseases.
  • Highlights shared and distinct features in epidemiology, anatomy, physiology, and immunopathology of the airways.

Context:

  • Allergic rhinitis significantly impacts asthma progression.
  • Conventional asthma treatments may fail without addressing concurrent upper airway disorders.

Purpose:

  • To underscore the importance of recognizing and managing upper airway diseases in refractory asthma.
  • To advocate for a personalized therapeutic approach in managing airway inflammation.

Summary:

  • Asthma and allergic rhinitis share common pathways, necessitating integrated management.
  • Effective asthma control in non-responders requires addressing upper airway conditions.
  • Rational use of antihistamines, antileukotrienes, and corticosteroids, tailored to individual pathophysiology, is crucial.

Impact:

  • Informs clinical practice towards a holistic approach to airway diseases.
  • Improves therapeutic outcomes for patients with difficult-to-treat asthma.
  • Advances understanding of the upper-lower airway axis in respiratory conditions.