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Pulsatile roller pump perfusion is safe in high risk patients
M Kocakulak1, S Küçükaksu, E Pişkin
1Başkent University, Biomedical Engineering Department, Ankara, Turkey. mustafak@baskent.edu.tr
The International Journal of Artificial Organs
|June 19, 2004
Summary
This study found that using a pulsatile roller pump during cardiopulmonary bypass is safe for high-risk patients. The technique showed no issues with emboli, hemolysis, or technical problems, proving reliable for open heart surgery.
Area of Science:
- Cardiovascular Surgery
- Biomedical Engineering
- Anesthesiology
Background:
- Cardiopulmonary bypass requires reliable arterial pumps.
- High-risk patients undergoing open heart surgery present unique challenges.
- Pulsatile perfusion aims to mimic physiological blood flow.
Purpose of the Study:
- To evaluate the safety and efficacy of a pulsatile roller pump (Sarns 8000) in high-risk patients.
- To assess blood cell depletion and hemolysis during pulsatile perfusion.
- To compare pulsatile versus non-pulsatile perfusion in this patient cohort.
Main Methods:
- A randomized clinical study involving 40 high-risk patients (COPD or chronic renal failure).
- Use of the Sarns 8000 roller pump with a pulsatile control module.
- Blood samples analyzed for hematocrit and plasma free hemoglobin at multiple time points.
Main Results:
- Pulsatile roller pump perfusion was found to be safe in high-risk patients undergoing cardiopulmonary bypass.
- No instances of emboli, hemolysis, or technical difficulties were encountered.
- Hematocrit and plasma free hemoglobin levels remained within acceptable ranges.
Conclusions:
- The Sarns 8000 pulsatile roller pump is a safe, simple, and reliable technique for open heart surgery.
- Pulsatile perfusion is well-tolerated by high-risk patients.
- This method can be readily implemented in clinical practice.