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Updated: Aug 23, 2026

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause
Published on: August 13, 2019
Cross-sectional study of differences in speech understanding between users and nonusers of estrogen replacement
1Department of Communication Disorders, University of Massachusetts at Amherst, Amherst, Massachusetts 01003-0410, USA. khelfer@comdis.umass.edu
Abstract:
The purpose of this study was to examine whether women who use estrogen replacement therapy (ERT) differ from women not using ERT on several measures of speech understanding. Participants (n = 38, 60 to 74 years) completed a battery of tests including pure-tone audiometry, the Dichotic Sentence Identification (DSI) test, a test of auditory-only and auditory-visual sentence recognition, and a measure of speech understanding in reverberation. In general, women who used ERT were better able to understand distorted speech than were nonusers of ERT.