The future of wavefront sensing and customization

The possibility of achieving supernormal vision in terms of acuity and contrast has fueled the imagination and creativity of vision researchers to pursue the goal of customized wavefront refractive surgery. This goal is achieved by generating an optimal ablation pattern based on individual anatomical and functional characteristics of the treated eye. However, increasing concerns regarding the clinical applicability of customized wavefront correction have emerged, and the possibility of achieving supernormal vision in all patients has been challenged. It is by understanding current optical, physiologic,and technological challenges faced by treating physicians and basic researchers that we can develop clear objectives for the future development of customized refractive surgery.