Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Dynamics of insertion sequence elements during experimental evolution of bacteria.

Dominique Schneider1, Richard E Lenski

  • 1Laboratoire Adaptation et Pathogénie des Microorganismes, CNRS UMR5163, Université Joseph Fourier, 38041 Grenoble Cedex 9, France. dominique.schneider@ujf-grenoble.fr

Research in Microbiology
|June 23, 2004
PubMed
Summary

Insertion sequence (IS) elements drive microbial adaptation and evolution. These mobile genetic elements serve as markers for genomic changes and generate beneficial mutations that enhance organismal fitness in experimental evolution studies.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The changing roles of Escherichia coli.

Nature microbiology·2025
Same author

The evolution of robustness and fragility during long-term bacterial adaptation.

Proceedings of the National Academy of Sciences of the United States of America·2025
Same author

Confronting risks of mirror life.

Science (New York, N.Y.)·2024
Same author

Pathogen contingency loci and the evolution of host specificity: Simple sequence repeats mediate Bartonella adaptation to a wild rodent host.

PLoS pathogens·2024
Same author

Effects of periodic bottlenecks on the dynamics of adaptive evolution in microbial populations.

Microbiology (Reading, England)·2024
Same author

Changing fitness effects of mutations through long-term bacterial evolution.

Science (New York, N.Y.)·2024

Area of Science:

  • Microbial Evolution
  • Genomics
  • Molecular Biology

Background:

  • Michel Blot's research focused on microbial evolution, specifically insertion sequence (IS) elements and experimental evolution.
  • Insertion sequence (IS) elements are mobile genetic elements with significant roles in host genome evolution.
  • Experimental evolution allows direct observation of genomic and phenotypic changes over time.

Purpose of the Study:

  • To review the intersection of IS element behavior and experimental evolution research.
  • To highlight the role of IS elements in microbial adaptation and host evolution.
  • To demonstrate the utility of IS elements in studying evolutionary dynamics.

Main Methods:

  • Literature review synthesizing research on IS elements and experimental evolution.

Related Experiment Videos

  • Analysis of IS element behavior within the context of laboratory-based evolutionary experiments.
  • Examination of IS elements as indicators of genomic alteration.

    • Main Results:

    • IS elements are valuable markers for detecting genomic changes during experimental evolution.
    • IS elements contribute to the generation of beneficial mutations.
    • These mutations enhance organismal fitness and evolutionary adaptation.

    Conclusions:

    • IS elements are key drivers of evolutionary adaptation in microbes.
    • Experimental evolution provides a powerful framework for studying IS element dynamics.
    • The dual role of IS elements as mutagens and evolutionary markers is crucial for understanding microbial evolution.