Related Experiment Video
Updated: Aug 23, 2026

Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries
Published on: March 31, 2021
[Protection of tooth protecting spray against dental carries]
Yuhong Li1, Xinlan Li, Chenrui Gong
1Hubei Center for Disease Control and Prevention, Wuhan 430079, China.
Objective:
To investigate the growth, adherence and soul production of streptococcus mutans incubated with olitin tooth protecting spray and the effect of specific sample against dental caries.
Methods:
Streptococcus mutans were cultured with the sample of Olitin tooth protecting spray. After culturing, S. mutans were observed by Gram stain and by spectrophotometer, and the percentages of the adherent S. mutans were calculated. 40 Wistar rats were divided into 4 groups: group A was control group; group B,C,D was low, middle, high test group respectively. All test groups received samples. The sum of the caries scores was assessed by the Keyes' procedure.
Results:
The sample did not inhibit the growth of S. mutans, but the long chain was occurred. The adherence of S. mutans cells on the glass was decrease, the pH value was increase to above 6.0. There was a significant lower mean of caries score of test group than control group.
Conclusion:
The sample can prevent the development of dental caries in this experiment. The mechanism may relate with the decrease of adherence of S. mutans.
Related Concept Videos
Tooth Anatomy
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or grinding food.
Teeth
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin and...
Minerals
The Oral Microbiota
Waterproofing and Anti-Bacterial Admixtures in Concrete
Waterproofing admixtures render concrete hydrophobic,...
Personal Protective Equipment
