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Torulopsis glabrata vertebral osteomyelitis.
P G Owen1, B K Willis, E C Benzel
1Department of Neurosurgery, University of New Mexico School of Medicine, Albuquerque 87131-5341.
Journal of Spinal Disorders
|September 1, 1992
Summary
A rare case of Torulopsis glabrata osteomyelitis in the thoracic spine caused spinal cord compression. Prompt treatment involving surgery and antifungal therapy led to successful recovery and pain relief.
Area of Science:
- Medical Mycology
- Infectious Diseases
- Spinal Surgery
Background:
- Torulopsis glabrata (Candida glabrata) osteomyelitis is a rare fungal infection.
- Spinal infections can lead to severe neurological complications like myelopathy.
- Predisposing factors include diabetes, prior surgery, and central venous catheterization.
Observation:
- A patient with diabetes and a history of abdominal surgery presented with thoracic spine osteomyelitis.
- The infection caused significant spinal cord compression and myelopathy.
- The patient had undergone intravenous catheterization with hyperalimentation.
Findings:
- Successful management was achieved through surgical decompression, debridement, and curettage.
- Postoperative immobilization and systemic amphotericin B therapy were crucial.
- The patient experienced pain relief, recovered spinal cord function, and healed uneventfully.
Implications:
- This case highlights the unpredictable and progressive nature of T. glabrata osteomyelitis.
- Prompt and aggressive therapeutic intervention is essential for favorable outcomes.
- Close monitoring is critical in managing this rare but serious infection.