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Identifying gaps between guidelines and clinical practice in the evaluation and treatment of patients with
Cathy B Spranger1, Andrea J Ries, Carrie A Berge
1Department of Internal Medicine, Division of Cardiology, University of Texas Southwestern Medical Center, Dallas 75235-8586, USA.
Insights
Many patients have uncontrolled hypertension due to poor adherence to clinical guidelines. Key JNC VI recommendations for blood pressure staging and medication titration are not consistently applied in primary care settings.
Area of Science:
- Cardiology
- Public Health
- Clinical Practice Guidelines
Background:
- Hypertension management remains a significant challenge, with a majority of patients failing to achieve target blood pressure levels despite available treatments.
- The Sixth Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC VI) provides evidence-based guidelines for hypertension management.
Purpose of the Study:
- To identify specific recommendations from the JNC VI guidelines that are not being effectively implemented in clinical practice.
- To assess the gap between JNC VI recommendations and actual patient care in primary care settings.
Main Methods:
- A retrospective chart review of 249 newly diagnosed hypertension patients across six community-based primary care clinics.
- Analysis of patient medical records over an 18-month follow-up period using a chart review instrument derived from JNC VI tables.
Main Results:
- Physician practices frequently deviated from JNC VI guidelines, including initial blood pressure staging based on single readings (85%) and low rates of recommended electrocardiograms (11%) and laboratory tests (approx. 50%).
- After 18 months, 40% of patients remained on monotherapy, and only 33% achieved the target blood pressure of <140/90 mm Hg.
- While patients with diabetes received appropriate renin-angiotensin system inhibitors, the average number of prescribed medications per patient was low (1.7).
Conclusions:
- Essential JNC VI components, such as accurate blood pressure staging, comprehensive cardiovascular risk assessment, and medication titration to achieve goals, are poorly translated into practice.
- Addressing these deficits requires the development and implementation of innovative, multilevel interventions to improve hypertension care.
Purpose:
Hypertension remains uncontrolled in the majority of affected patients despite treatment. Our goal was to identify specific action items in the Sixth Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC VI) guidelines that are not being translated into clinical practice.
Methods:
We transformed the major JNC VI tables into a chart review instrument that was used to retrospectively analyze the medical records of 249 patients with newly diagnosed hypertension who had been followed for 18 months at one of six community-based primary care clinics.
Results:
The practices of physicians deviated from the guidelines in several ways. Hypertension was staged initially on a single blood pressure recording in 85% (n = 212) of patients. No electrocardiogram was ordered for 89% (n = 221) of patients, while other mandatory laboratory tests were ordered for about 50%. After 18 months, 40% (72/179) of patients for whom prescription records were identified were still on monotherapy, and target blood pressure (<140/90 mm Hg) was achieved in only 33% (83/249) of patients. All of the 35 patients with diabetes received an angiotensin-converting enzyme inhibitor or angiotensin receptor blocker, but only 1.7 medications were prescribed per patient at study end.
Conclusion:
In this clinic system, staging of blood pressure with multiple measurements, thorough assessment of global cardiovascular risk, and titration of multiple antihypertensive medications to achieve blood pressure goal are components of the JNC VI guidelines that are not well translated into clinical practice. Overcoming these practice defects will require innovative multilevel interventions.
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