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Updated: Aug 11, 2026

Flow Cytometry to Estimate Leukemia Stem Cells in Primary Acute Myeloid Leukemia and in Patient-derived-xenografts, at Diagnosis and Follow Up
Published on: March 26, 2018
Deletion 12p in de novo acute myeloid leukemia. An association with early progenitor cell
1Department of Pathology, Queen Mary Hospital, University of Hong Kong.
Abstract:
Deletion of the short arm of chromosome 12 as the sole karyotypic abnormality was found in three cases of acute myeloblastic leukemia (AML). In contrast to what has previously been reported in the literature, none of our cases had an antecedent history of myelodysplasia or toxic exposure, and basophilia was absent. Two cases were terminal deoxynucleotidyl transferase (TdT) positive, suggesting involvement of an early progenitor cell.
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