Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Inflammatory response after neurosurgery.

Leman K Mutlu1, Christian Woiciechowsky, Ingo Bechmann

  • 1Department of Cell and Neurobiology, Institute of Anatomy, Humboldt University Medical School-Charité, Berlin, Germany.

Best Practice & Research. Clinical Anaesthesiology
|June 24, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Expression of GPR34 in microglia remains stable in human Alzheimer's disease.

Acta neuropathologica·2026
Same author

A deep-learning framework reveals whole-body perturbations at cell level.

Nature·2026
Same author

Uniportal full-endoscopic decompression of the posterior cranial fossa: a comparative anatomical study of defect assessment using ultrasonography versus radiography and computed tomography.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery·2026
Same author

Diet-Driven Microglial Activation: Region-Specific Neuroinflammation in the Mouse Brain.

Brain sciences·2026
Same author

Modulating food intake by nasal application of peptides targeting melanocortin 4 receptor and ghrelin receptor systems.

Brain communications·2026
Same author

Proteomic comparison of human brain tissue preservation methods.

Journal of proteomics·2026
Same journal

Reimagining cardiac surgery-the emerging role of prehabilitation and risk optimization.

Best practice & research. Clinical anaesthesiology·2026
Same journal

Prehabilitation and enhanced recovery after cardiac surgery.

Best practice & research. Clinical anaesthesiology·2026
Same journal

The role of biomarkers in the preoperative evaluation of cardiac surgical patients - A narrative review.

Best practice & research. Clinical anaesthesiology·2026
Same journal

Magic in a bottle? A Focused review of factor concentrates for the intraoperative treatment of acquired coagulopathy - Fibrinogen concentrate, prothrombin complex concentrate, and recombinant activated factor VII.

Best practice & research. Clinical anaesthesiology·2025
Same journal

ESAs in perioperative anemia management: Who, what, how and why?

Best practice & research. Clinical anaesthesiology·2025
Same journal

Does patient blood management represent good value for money?

Best practice & research. Clinical anaesthesiology·2025
See all related articles

Central nervous system (CNS) inflammation has a dual role in recovery after injury, potentially worsening or improving outcomes. This review explores immune system interactions with the CNS, highlighting beneficial inflammation and therapeutic strategies.

Area of Science:

  • Neuroscience
  • Immunology
  • Cellular Biology

Background:

  • Central nervous system (CNS) inflammation is a complex process with significant implications for neurological conditions.
  • The CNS, traditionally considered non-regenerative, exhibits a dynamic interplay between immune responses and neural tissue.
  • Recent decades have seen a surge in research elucidating the multifaceted roles of inflammation in the CNS.

Purpose of the Study:

  • To review current literature on immune system and CNS interactions in health and disease.
  • To provide an overview of the cellular and molecular mechanisms underlying CNS inflammation.
  • To discuss the implications of inflammation for CNS regeneration and functional recovery.

Main Methods:

  • Literature review of scientific articles and research papers.

Related Experiment Videos

  • Synthesis of information on cellular and molecular components of CNS inflammation.
  • Analysis of studies investigating systemic immunodepression post-neurotrauma and neurosurgery.

    • Main Results:

    • CNS inflammation presents a dual role, capable of both exacerbating and promoting regeneration and functional outcomes.
    • Neurotrauma and neurosurgery can induce systemic immunodepression, impacting CNS recovery.
    • A delicate balance exists within CNS immune responses, with inflammation offering potential therapeutic benefits.

    Conclusions:

    • Understanding the intricate balance of immune responses in the CNS is crucial for developing effective therapeutic strategies.
    • Targeting inflammatory pathways may offer novel approaches to enhance CNS repair and functional recovery.
    • Further research into the beneficial aspects of CNS inflammation is warranted for advancing neuroregenerative medicine.