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Updated: Jul 29, 2026
Formation of Ordered Biomolecular Structures by the Self-assembly of Short Peptides
Published on: November 21, 2013
Doughnut-shaped peptide nano-assemblies and their applications as nanoreactors
Ramin Djalali1, Jacopo Samson, Hiroshi Matsui
1Department of Chemistry and Biochemistry at Hunter College and the Graduate Center, The City University of New York, New York, New York 10021, USA.
Abstract:
Doughnut-shaped nanoreactors, peptide nano-doughnuts, were self-assembled from peptides and organic Au salts. We demonstrated that monodisperse Au nanocrystals were synthesized inside the cavities of peptide nano-doughnuts by the reduction of Au ions and the size of the Au nanocrystal was controlled by the cavity dimension. The Au nanocrystals inside the nano-doughnuts were extracted by destroying the nano-doughnuts via long UV irradiation (>10 h). These features may allow the peptide nano-doughnuts to be applied in the fields of nanomaterial syntheses, controlled release systems, and drug delivery.
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